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AREVIR-GenaFor-Meeting 2013

Program

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Donnerstag, 11. April 2013

Zeit Vorträge

09:00 - 09:15

Opening Remarks
Thomas Puy-Brill / Odysseum, Köln

09:15 - 11:15

Chair: Ulrike Protzer, Maria Neumann Fraune
State of ART in HBV /HDV - HOPE
Speakers: Dieter Glebe, Jens Verheyen, Bastian Beggel, Michael Manns, Florian van Bömmel, Michael Chudy

 

Lessons learned during the HOPE-Project: Which role have HBV mutations in the times of tenofovir and entecavir?
Florian van Bömmel
University Hospital Leipzig Hepatology Section

 

Phenotypic evaluation of resistance profiles of HBV polymerase against Lamivudine reveals an unexpected resistance against Adefovir and Entecavir
Dieter Glebe
Institute for Medical Virology, National Reference Centre for Hepatitis B and D Viruses, Justus-Liebig-Universität Gießen, Germany

 

Novel rtM204 Mutations in HBV Polymerase Confer Reduced Susceptibility to Adefovir and Tenofovir
Ke Zhang
Institute of Virology Technische Universität München

 

Inferring Linkage Information from Sequencing Chromatograms
Bastian Beggel
Max-Planck-Institute for Informatics Saarbrücken

 

HBV: clinical implications beyond drug resistance
Jens Verheyen
Institut für Virologie Universitätsklinikum Essen

 

Key patterns of mutations in HBx and in Pre-S1/2-S regions involved in mechanisms underlying HBV-induced hepatocellular carcinoma in vivo
Romina Salpini
Tor Vergata University, Rome

 

DEVELOPMENT OF AN INTERNATIONAL STANDARD FOR HEPATITIS D VIRUS RNA
Michael Chudy
Paul-Ehrlich-Institut Federal Institute for Vaccines and Biomedicines

11:15 - 11:45

Coffee break

11:45 - 13:30

Chair: Johannes Bode, Tobias Goeser
State of ART in HCV - PEPSI
Speakers: Christoph Jochum, Daniel Rupp, Anna Marie Sikorski, Thomas von Hahn

 

Hepatitis C - Current Therapy
Christoph Jochum
Universitätsklinik Essen

 

Phenotypic HCV-NS3-PI-Resistance Test
Daniel Rupp
Uniklinik Köln

 

HEPATITIS C VIRUS - RESISTANCE SCREENING
Anna Maria Sikorski
Uniklinik Köln

 

Drugs for chronic hepatitis - The next 5 years
Thomas von Hahn
Medizinische Hochschule Hannover

13:30 - 14:30

Lunch

14:30 - 15:15

Chair: Stefan Esser
HIV-1 -2 diagnostics and therapy - state of ART, HIV-2 Algorithm (HIV-GRADE / CHAIN activities)
Speakers: Martin Stürmer, Martin Obermeier, Hauke Walter

 

HIV-1 and HIV-2 diagnostics
Hauke Walter
Medizinisches Labor Dr. Berg

 

HIV2EU collaboration - Resistance algorithm
Martin Obermeier
Medizinisches Labor Dr. Berg

 

HIV-GRADE: Rules-Based Genotypic HIV Drug-Resistance Interpretation under Consideration of Bioinformatic Knowledge
Alejandro Pironti
Max-Planck-Institute for Informatics Saarbrücken

15:15 - 17:00

Chair: Thomas Lengauer, Thomas Klimkait
Geno2pheno - the revolution of a concept - basic science and clinical routine
Speakers: Thomas Lengauer and coworkers

 

Prediction of HIV viral tropism based on NGS data
Nico Pfeifer
Max-Planck-Institute for Informatics Saarbrücken

 

Effects of Sequencing Errors on geno2pheno[coreceptor]
Alejandro Pironti
Max-Planck-Institute for Informatics Saarbrücken

 

Structural study on HIV viral tropism
Olga Kalinina
Max-Planck-Institute for Informatics Saarbrücken

 

Cross-country HIV transmission: A pan-European phylodynamic study
Prabhav Kalaghatgi
Max-Planck-Institute for Informatics Saarbrücken

 

Reconstruction of the Intra-Host Evolution of HCV
Mathieu Flinders
Max-Planck-Institute for Informatics Saarbrücken

17:00 - 17:15

Coffee break

17:15 - 18:00

Chair: Alexander Thielen
Ultra deep sequencing, Proviral DNA analysis
Speakers: Martin Däumer, Bastian Beggel, Rolf Kaiser

 

Next generation sequencing to determine HIV-1 coreceptor tropism
Martin Däumer
Institut für Immunologie und Genetik, Kaiserslautern

 

Improvement in the Cost of DNA sequencing
Bastian Beggel
Max-Planck-Institute for Informatics Saarbrücken

 

Low Viral Load
Rolf Kaiser
Uniklinik Köln

 

Freitag, 12. April 2013

Zeit Vorträge

09:00 - 10:00

Chair: Eugen Schülter
EuResist
Speakers: Maurizio Zazzi, Anders Sonnerborg
Rolf Kaiser: The EucoHIV project

 

HIV-1 subtype C in Ethiopia and India
Anders Sönnerborg
Div. of Clinical Microbiology and Infectious Diseases, Karolinska Institute, Sweden

 

Hepatitis C and perspective for EuResist
Maurizio Zazzi
Dept. of Microbiology, University of Siena, Italy

 

eucohiv - European HIV Coreceptor Study Panel
Rolf Kaiser
Institute of Virology, University of Cologne, Germany

10:00 - 11:00

Chair: Thomas Lengauer, Mark Oette
Are the current strategies for clinical studies still up to date or yesterdays painful burden?
Speakers: Markus Löffler

 

Personalized Molecular Medicine
Markus Löffler
Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig

11:00 - 11:30

Coffee break

11:30 - 13:30

Chair: Dieter Häussinger, Herbert Pfister
RESINA and RKI - seroconverter study
Speakers: Mark Oette, Alejandro Pironti, Karolin Meixenberger, Klaus Jansen, Björn Jensen, Glenn Lawyer, Daniel Schmidt

 

Coinfections with HBV, HCV and Syphilis in MSM with known date of HIV 1- seroconversion in Germany
Klaus Jansen
Robert Koch-Institute, Germany

 

Resistance testing practices and prevalence of HIV drug resistance in the German ClinSurv resistance study
Daniel Schmidt
Robert Koch-Institute, Germany

 

CCR5 longitudinal - was tun bei widersprüchlichen Ergebnissen ?
Björn Jensen
Klinik für Gastroenterologie, Hepatologie und Infektiologie, Uniklinik Düsseldorf

 

Time on Drug - Analysis of EIDB therapy data
Eugen Schülter
Institute of Virology, University of Cologne, Germany

13:30 - 14:30

Lunch

14:30 - 15:45

Workshop sessions part 1 (select one)
1. HIV-resistance: Stefan Scholten, Alejandro Pironti, Hauke Walter
2. HIV tropism: Björn Jensen, Martin Obermeier, Alexander Thielen
3. HBV resistance and escape: Andreas Erhardt, Bastian Beggel, Maria Neumann-Fraune
4. HCV resistance: Katja Römer, Nico Pfeifer, Saleta Sierra Aragon

 

HIV-1 Tropism - Arevir workshop
Martin Obermeier

 

Case I: Nonresponder
Katja Römer

 

Case II: Side effects
Katja Römer

 

Case III: Co-Infected
Katja Römer

15:45 - 16:30

Coffee break

16:30 - 17:30

Workshop sessions part 2 (select one)
1. HIV-resistance: Stefan Scholten, Alejandro Pironti, Hauke Walter
2. HIV tropism: Björn Jensen, Martin Obermeier, Alexander Thielen
3. HBV resistance and escape: Andreas Erhardt, Bastian Beggel, Maria Neumann-Fraune
4. HCV resistance: Katja Römer, Nico Pfeifer, Saleta Sierra Aragon

17:30 - 18:00

Summary of the workshops and closing remarks

Rolf Kaiser

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