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AREVIR-GenaFor-Meeting 2011


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Donnerstag, 05. Mai 2011

Zeit Vorträge

09:00 - 09:15

Opening Comments
U. B. Kaup / Stiftung caesar

09:15 - 10:45

Chair: Dieter Glebe, Maria Neumann-Fraune
Hepatitis B
HBV: therapy updates
HBV: Resistance testing, Determination of Genotype Escape-Variants
Speakers: Bastian Beggel, Florian van Bömmel, Wolfram Gerlich


Long Term Management of chronical HBV
Slides missing

Florian van Bömmel


Role of mutations outside the RT-domain of HBV polymerase on antiviral resistance
Dieter Glebe


Update on geno2pheno[HBV]
Bastian Beggel


Covalently Closed Circular (ccc) DNA in the Clinical Setting
Karsten Wursthorn

10:45 - 11:00

Coffee break

11:00 - 12:15

Chair: Tobias Goeser / Rolf Kaiser
Hepatitis C
HCV: Basics
HCV: new drugs
HCV: Resistance testing


Hepatitis C Virus: Basics & Antiviral Therapy
Ralf Bartenschlager


Hepatitis C Virus: Pre PI Screening Project
Anna Maria Sikorski


Interpreting HCV genotypes
Sven-Eric Schelhorn


HCV NS3/4A protease inhibitors for the treatment of HCV infected patients
Oliver Lenz


Slides missing
Müller (MSD)


The Road Ahead: Reassessing Unmet Needs in HCV Management
Stefan Zeuzem (Rolf Kaiser)

12:15 - 13:30

Chair: Thomas Klimkeit / Nadine Lübke
Speakers: Valentina Svicher, Alexander Thielen, Nico Dybowski, Björn Jensen


Tropism Testing: Facts - Challenges - Vision
Thomas Klimkeit


geno2pheno [coreceptor]
Alexander Thielen


Correlating Genotypic Tropism Prediction with the Virological Response to MVC Treatment
Nikolaj Dybowski


Physicochemical and structural properties determining HIV-1 coreceptor usage
Kasia Bozek


CCR5 Antagonists in Clinical Practice
Björn Jensen


Adding HIV-1 genetic variability to the study of the local epidemic and co-receptor usage in recently diagnosed individuals
Kristen Chalmet


Tropism Testing: Who needs a Phenotype...
Thomas Klimkeit


Enhancement of genotypic test for tropism determination: the role of the oscar project
Claudia Alteri


European Coreceptor Analyses
Rolf Kaiser

13:30 - 14:30


14:30 - 15:15

Chair: Rolf Kaiser


Introduction to the European Society for Antiviral Resistance (ESAR)
Annemarie Wensing


Characterization of the resistance profile of TMC278
Johan Vingerhoets


ABL - TherapyEdge
Chalom Sayada

15:15 - 15:40

Chair: Herbert Pfister
HIV - resistance


Predicting response to HIV therapy by computational modeling of large clinical datasets
Brendan Larder

15:30 - 17:30

Chair: Lutz Gürtler / Patrick Braun
HIV Low viral load
Qiagen, Roche, Siemens and Abbott assays presented Presentation low viral load assays
Clinical case


Low level viremia
Stefan Esser


Anne Beyou-Zuliani


QIAsymphony RGQ - The Power of Flexibility
Gavin Wall


Highly sensitive detection of HIV-1 viral load - COBAS® AmpliPrep/COBAS®
Dorothea Sizmann


Abbott RealTime HIV-1
Birgit Reinhardt


Low-level Viremia below 50 cps/mL in treated HIV-infected patients predicts viral load rebound above 400 cps/mL independently of adherence levels
Paola Vitiello


Comparison of HIV-1 Viral Load samples between RealTime (Abbott) and COBAS TaqMan (Roche)
Gudrun Naeth


Hauke Walter

17:30 - 18:30

Chair: Sandra Müller
Basics science
Speakers: Evrim Anadol, Renate König, Carsten Münk


Comparative study of intra-host HIV evolution: Emergence of viral diversity
Miriam Carbon-Mangels


HIV-1's different ways to survive against hostile APOBEC3 proteins
Carsten Münk


Freitag, 06. Mai 2011

Zeit Vorträge

09:00 - 10:00

Chair: Hauke Walter, Alexander Thielen
New sequencing technologies replacing Sanger seq?


Next generation sequencing technologies replacing Sanger sequencing?
Martin Däumer

10:00 - 11:00

Chair: Mark Oette / Eugen Schülter
Databases and projects
RKI-CLINSERV/seroconverter study
Data from the RESINA cohort


Trends in transmission of resistant HIV and HIV-1 subtypes
Claudia Kücherer


Antiretroviral treatment patterns in the ClinSurv HIV Cohort
Barbara Bartmeyer

11:00 - 13:00

Protocols, interpretation, clinical application


1.) CoreceptorSlides missing
Martin Obermeier, Alexander Thielen, Ramona Pauli


2.) HBVSlides missing
Andreas Erhardt, Jens Verheyen, Bastian Beggel


3.) HCV Slides missing
Saleta Sierra-Aragon, Christoph Boesecke, Sven Eric Schelhorn

13:00 - 13:30

Chair: Rolf Kaiser
Is resistance disappearing ?


Is HIV-1 drug resistance disappearing ?
Andrea De Luca

13:30 - 14:30


14:30 - 18:00

Chair: Maurizio Zazzi, Francesca Incardona
International EuResist meeting Therapy-Naïve-Tools
Prediction based on therapy history
HIV resistance, treatment perspectives and data collection in Russia, Tanzania, Vietnam, Kenya, Ethiopia, India


EuResist present and future
Anders Sonnerborg


Applying HIV Bioinformatics to Clinical Practice: What Will The Future Bring?
Thomas Lengauer, Max-Planck-Institute for Informatics (Saarbrücken)


A Tool for Predicting the Success of First-Line Antiretroviral Therapies
Alejandro Pironti, Max-Planck-Institute for Informatics (Saarbrücken)


History-aware models for predicting outcomes of HIV combination therapies
Jasmina Bogojeska, Max-Planck-Institute for Informatics (Saarbrücken)


Impact of peer support on survival, virological treatment failure and resistance among HIV naïve patients - a randomized control trial in Vietnam
Do Duy Cuong, Karolinska Institutet Stockholm (Sweden)


Overview of HIV, Treatment, Resistance and Prospective Data Collection in Tanzania
Doreen Mloka, Muhimbili University of Health Sciences (Tanzania)


Historical Background of HIV in Kenya
Washington Njogu, Ruaraka Neema Hospital (Kenya)


HIV treatment perspectives, resistance and data collection in Kenya
Matilu Mwau, KEMRI (Kenya)


HIV resistance, treatment perspectives, and data collection in Ethiopia
Wondwossen Amogne


HIV treatment & ARV resistance issues in India
Dr. N. Kumarasamy, Chief Medical Officer, YRG Centre for AIDS Research and Education VHS (Chennai, India)


HIV-1 Molecular Epidemiology and Drug Resistance in India
Ujjwal Neogi, St. John’s Medical College and Hospital (Bangalore, India)

18:00 - 18:30

Rolf Kaiser

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